解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::Kisspeptin is distributed not only in brain areas for regulating reproduction but also in nuclei involved in feeding control. Whether kisspeptin alters food intake is unknown in mice. We examined how kisspeptin-10 influences feeding after intracerebroventricular injection in mice using automated monitoring. Kisspeptin...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e32834558df
更新日期:2011-03-30 00:00:00
abstract::The neural origins of the cortical response to rare sensory events remain poorly understood. Using simultaneous event-related potentials and magnetic resonance imaging, we investigated the anatomical profile of regional activity at various processing stages during performance of auditory and visual variants of an oddb...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e3283435c37
更新日期:2011-02-16 00:00:00
abstract::α-Gustducin (Gα-gust) is the α subunit of the heterotrimeric G-protein complex specific for taste receptor cells of the tongue. However, it has been shown to be present in ectopic regions, such as airways and digestive tract. Recently, Gα-gust was found within neurons in various regions of the mouse brain. In this stu...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e328343701f
更新日期:2011-02-16 00:00:00
abstract::Interleukin-6 (IL-6) is a proinflammatory cytokine known to modulate neurogenesis. We presently evaluated neural progenitor proliferation, survival, and phenotypic maturation in the hippocampal dentate gyrus, subventricular zone, and the posterior periventricle in the brains of IL-6 knockout mice and their wild-type l...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e3283430a44
更新日期:2011-02-16 00:00:00
abstract::This study compared the visuospatial asymmetries in children with dyslexia and healthy children by using the manual line bisection task, and investigated the processing of spatial context with a 'local' cueing paradigm consisting of geometric symbols placed on the extremities of the lines. The performance between heal...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e328342d2df
更新日期:2011-01-26 00:00:00
abstract::Blood oxygen level dependent MRI was used to test whether cocaine-stimulated mesolimbic activity varied with sexual receptivity. Rats were randomly screened for lordotic responses and were then imaged for their responses to centrally administered cocaine. We observed that female rats expressing no lordosis showed a gr...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e3283416f81
更新日期:2011-01-05 00:00:00
abstract::Piccolo is one of the components of the active zone at chemical synapses and regulates the transport of synaptic vesicles. The piccolo C2A domain is an important calcium sensor and binds with phosphatidylinositol or synaptotagmin-1. Recently, clinical studies suggested that a single nucleotide polymorphism in the picc...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e3283411685
更新日期:2010-12-29 00:00:00
abstract::Menthol is known as an agonist for cold-sensitive transient receptor potential channels (TRPM8) and also as a direct modulator of GABA channels. We examined the effects of menthol on respiratory rhythm generation in the brainstem-spinal cord preparations isolated from newborn rats. Menthol decreased respiratory rhythm...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e3283405bad
更新日期:2010-12-08 00:00:00
abstract::Hydrogen peroxide (H₂O₂) is a ubiquitous reactive oxygen species that can induce several inner ear disorders. In this study, we recorded the potassium (K) currents in acutely isolated inner hair cells of guinea pig cochlea, and investigated the effects of H₂O₂. We also observed the morphological changes in inner hair ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e32833fcb56
更新日期:2010-11-17 00:00:00
abstract::Timing of the mammalian circadian clock of the suprachiasmatic nucleus (SCN) is regulated by photic input from the retina. Retinorecipient units entrain rhythmicity of SCN pacemaker cells in part through their release of vasoactive intestinal polypeptide (VIP). The underlying nature of this process is conjectural, how...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e32833fcba4
更新日期:2010-11-17 00:00:00
abstract::We recorded multiple unit activities of the CA1 region of the intermediate hippocampus and prelimbic area of the prefrontal cortex, and evoked responses in the prefrontal cortex by hippocampal stimulation in urethane-anesthetized rats. The multiple unit activities between these regions showed significant peaks of cros...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e32833f4788
更新日期:2010-10-27 00:00:00
abstract::We investigated the effects of chemical hypoxia on the central pattern generator controlling swimming in stage 42 Xenopus laevis larvae. We recorded motoneuron activity from ventral roots of immobilized tadpoles and evoked swim episodes by brief electrical stimulation of the tail skin. In the presence of the metabolic...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e32833e332d
更新日期:2010-10-06 00:00:00
abstract::In the visual modality adaptation to high temporal frequency can result in spatially localized apparent duration compression. The principal point of adaptation is thought to be early in the visual system, at which point temporal information is encoded within sustained (parvocellular) and transient (magnocellular) chan...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e32833d6bcb
更新日期:2010-09-15 00:00:00
abstract::The balance between heat production (metabolism) and heat removal (blood flow) helps in keeping the temperature of the brain constant. In patients with moyamoya disease, this balance may be disturbed. The purpose of this study was to assess the thermal pathophysiology of the brain in patients with moyamoya disease. Th...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e32833d6b7a
更新日期:2010-09-15 00:00:00
abstract::During the development of central nervous system, radial glial cells support target-specific neuronal migration. We recently reported that after implantation of chitosan channels with complete spinal cord transection, the tissue bridging the spinal cord stumps contained axons and radial glial cells. The purpose of thi...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e32833d9695
更新日期:2010-09-15 00:00:00
abstract::Dopamine D2 receptor (D2R) signalling is implicated in limbic seizure propagation and seizure-induced neurodegeneration. D2R-/- mice display increased susceptibility to kainic acid (KA) seizures and seizure-induced apoptosis of hippocampal neurons. Here we further investigated the molecular pathways of KA-induced apop...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e32833d5891
更新日期:2010-08-23 00:00:00
abstract::We examined the induction of progesterone receptor-immunoreactive (PR-ir) cells by estrogen in the rat preoptic area and ventromedial hypothalamic nucleus. Ovariectomized young (3-month-old) and old (24-month-old) female rats were treated with estrogen or cholesterol for 4 days. Estrogen significantly increased PR-ir ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e32833c5b6f
更新日期:2010-08-04 00:00:00
abstract::After amputation of an arm the sensory map of the body changes radically, causing the sensory input from face to 'invade' the original hand area in the brain. As a result, touching the face of the amputee evokes tactile sensations on the phantom. These sensory referrals from the face to phantom hand occur in a stable,...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e32833be9ab
更新日期:2010-07-14 00:00:00
abstract::Recent studies of electroencephalogram event-related potentials reported aberrant feedback-related negativity (FRN) in neurological and psychiatric diseases, such as alcoholism and attention-deficit hyperactivity disorder. These diseases are characterized by high impulsivity. We investigated the relationship between F...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e32833bfd36
更新日期:2010-07-14 00:00:00
abstract::This study examined the basis for introducing an ignoring task during cortical evoked response audiometry (CERA) using the N1-P2 response. Healthy hearing participants were assigned to two groups with and without an ignoring task (ignoring and listening groups) during CERA whose outcomes were compared with the pure-to...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e32833b502a
更新日期:2010-07-14 00:00:00
abstract::We examined the protective effects of N-acetylcysteine (NAC) on the death of glia-free neurons in culture. Under normoxic conditions, the protection by NAC was observed only in cystine-free but not complete medium. When the cells were cultured under hypoxic conditions, NAC much elongated their survival even in the pre...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e328337765c
更新日期:2010-04-21 00:00:00
abstract::Face processing deficits are characteristic of autism spectrum conditions. However, event-related potential studies of autism spectrum conditions have found inconsistent results for the face selective N170 component. In this study, 15 adult males with autism spectrum conditions and 15 matched, typically developing con...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/wnr.0b013e328334311b
更新日期:2010-04-21 00:00:00
abstract::Prism adaptation reduces some symptoms of neglect; however the mechanisms underlying such changes are poorly understood. We suggest that prisms influence neglect by acting on dorsal stream circuits subserving visuomotor control, with little influence on perceptual aspects of neglect. We examined prism adaptation in th...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e328338592f
更新日期:2010-04-21 00:00:00
abstract::Male Bengalese finches sing complex song sequences during courtship. To examine the female perception of sequence complexity, we tested female auditory processing with respect to sequential differences in the caudomedial nidopallium and caudomedial mesopallium. Repeated song presentations caused lower expression of th...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e32833730b7
更新日期:2010-04-21 00:00:00
abstract::Prefrontal delay-period activity represents a neural mechanism for the active maintenance of information and needs to be controlled by some signal to appropriately operate working memory. To examine whether reward-delivery acts as this signal, the effects of delay-period activity in response to unexpected reward-deliv...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e32833776a3
更新日期:2010-03-31 00:00:00
abstract::Multiple regression voxel-based morphometry analyses were used to examine the relationship between regional gray matter volumes and neurocognitive performance in 10 patients with amnestic mild cognitive impairment and 20 healthy age-matched controls. Cognitive functioning was assessed with seven standardized neuropsyc...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e328335642a
更新日期:2010-03-10 00:00:00
abstract::Central sensitization is a fundamental mechanism contributing to acute and chronic pain conditions. Our previous studies have documented a glutamatergic, purinergic and glial-dependent central sensitization that can be induced in rat medullary dorsal horn nociceptive neurons by mustard oil application to the tooth pul...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e328336eecb
更新日期:2010-02-17 00:00:00
abstract::In the adult rat hippocampal formation, neurogenesis occurs in the dentate gyrus subgranular zone (SGZ). We used laser capture microdissection and an antidepressant-related genes microarray to analyze gene expression profiles of cells from the SGZ and from the outermost granule cell layer. Of the differentially expres...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e3283350b24
更新日期:2010-01-27 00:00:00
abstract::Beta-N-methylamino-L-alanine (BMAA) is a nonprotein amino acid that may be involved in neurodegenerative diseases. It is produced by a large variety of cyanobacteria and is found at high levels in the brains of Alzheimer's disease and amyotrophic lateral sclerosis patients. Although BMAA is clearly a neurotoxin, previ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e328333dfd5
更新日期:2010-01-06 00:00:00
abstract::We examined the effect of long-term potentiation (LTP) on paired-pulse responses across varied stimulus intensities and interstimulus intervals (ISIs), at ascending synapses from the intermediate and ventral hippocampus to the medial prefrontal cortex in urethane-anesthetized rats. LTP significantly shifted the median...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e3283344949
更新日期:2010-01-06 00:00:00
abstract::The hippocampus is well known to contribute to episodic memory encoding. Here we used functional magnetic resonance imaging to investigate the hippocampal response to exponentially varying encoding demands while forming associations between faces and names. We found that only the left hippocampus exhibited a stepped m...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e3283340d36
更新日期:2010-01-06 00:00:00
abstract::Recently, we have generated transgenic mice (designated as SJLB) carrying human N279K mutant tau, one of the tau mutations causing parkinsonism linked to chromosome 17 (FTDP-17). SJLB mice mimic some features of behavioral alterations and neuronal pathology of patients with Alzheimer's disease. To investigate how tau ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e328333b0e0
更新日期:2009-12-09 00:00:00
abstract::Caffeine is a widely self-administered psychostimulant with purported neuroprotective and procognitive effects in rodent models of aging. The cholinergic basal forebrain is important for arousal and attention and is implicated in age-related cognitive decline. Accordingly, we determined the effects of caffeine on chol...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e3283329c3a
更新日期:2009-12-09 00:00:00
abstract::Inconsistencies in previous attempts to localize the N2 wave in the GO/NOGO task led to the present investigation. The inconsistencies were probably because of heterogeneity of psychological operations involved in GO/NOGO tasks. We applied the independent component analysis to a collection of individual event-related ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e3283309cbd
更新日期:2009-12-09 00:00:00
abstract::Perceptual regularities have been investigated intensely in music research but to a lesser extent in speech research possibly because of its irregular nature. People tend to rhythmize almost every given acoustic input though, even if one stimulus is physically identical to the next. Hence, perception of regularities s...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e328333b0c6
更新日期:2009-12-09 00:00:00
abstract::Age-related depletion of androgens in men results in functional impairments in androgen-responsive tissues, such as the brain, resulting in increased risk for Alzheimer's disease. To investigate the relationship between normal age-related hormone loss and Alzheimer's disease risk, we evaluated the brain and serum leve...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e328331f968
更新日期:2009-11-25 00:00:00
abstract::The relationship between cerebral ischemia and Alzheimer's disease has been evaluated extensively. However, the association between cerebral ischemia and the deposition of beta-amyloid (Abeta) remains to be clarified. Here, we used mice bilateral common carotid artery ligation model to investigate the alterations in m...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e328332024a
更新日期:2009-10-28 00:00:00
abstract::Learning and memory are cognitive functions commonly impaired after surgery, especially in elderly patients. Our aim was to evaluate the effect of sevoflurane anaesthesia on episodic-like memory in young and aged wild-type mice and mice with altered nicotinic cholinergic neurotransmission (beta2KO). Mice learned objec...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e328330cd2b
更新日期:2009-10-28 00:00:00
abstract::GLYX-13 (threonine-proline-proline-threonine-amide) is an amidated di-pyrrolidine that acts as a functional partial agonist at the glycine site on N-methyl-D-aspartate glutamate receptors (NMDARs). GLYX-13 can both increase NMDAR conductance at NR2B-containing receptors, and reduce conductance of non-NR2B-containing r...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e32832f5130
更新日期:2009-08-26 00:00:00
abstract::Reward-processing neurocircuitry has been delineated using verbal or visual processing and/or decision-making tasks. We examined more basic processes of listening to enjoyable music in healthy and depressed patients. The paradigm was passive, individualized, and brief. Sixteen depressed and 15 control individuals prov...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e32832f4da3
更新日期:2009-08-26 00:00:00